Earlier on Tuesday a separate Reuters witness reported scores of people running from the Arndale shopping centre, with some saying they had heard a big bang.
Manchester's Arndale Centre has been evacuated and one man has been arrested.
Conflicting reports suggested the incident might have been a false alarm amid high tensions following Monday's attack, the local media reported. The explosion occurred at around 10:30 pm on Monday night when Grande was concluding her concert with the last song.
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The unofficial death toll, however, was pegged around 10,000 as many bodies were never found. Although no casualties were reported, nearly 15 thousand tourists are stranded.
Many were confused with some visibly shaken and tearful.
Police in the northern English city of Manchester are investigating an incident at the Arndale shopping centre, an officer at the scene said on Tuesday. The shopping centre was evacuated by armed police but later reopened.
Unconfirmed reports say that a suspicious package was found in the food court.
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The evacuation is now ongoing.
Police gave the news moments after confirming another man had been arrested in connection to the concert attack.
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