Freeman High School is south of Spokane by about 30 minutes, off Highway 27.
Sacred Heart Hospital confirmed there were three patients in stable condition there, with reports from local media of up to six injured in total.
An automated warning that was reportedly repeating on law enforcement radio channels said, "Freeman High School".
A suspect was detained after multiple injuries were reported, according to NBC-affiliate KHQ.
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Freeman Middle School and Freeman Elementary school, both located in Spokane County, have been placed on lockdown, the sheriff's office wrote on Twitter.
She says classes were about to begin because it's a "late start" day.
Freeman Store says parents are meeting outside in the parking lot by Freeman High School.
Brian Schaeffer of the Spokane Fire Department told reporters that one person died in the shooting Wednesday morning.
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Parent Cheryl Moser told the paper her son called her from a classroom on the second floor after hearing gunshots. "You never think about something happening like this at a small school". After an hour, the school tweeted that the lockdown had been lifted.
"It's been wonderful, within probably 15-20 minutes of hearing about it, I'd already received a phone call, I'd already received a text message saying that their school is OK", she said. "We will provide info ASAP, please avoid area". Washington Democratic Gov. Jay Inslee took to Twitter to offer his support.
PBS NewsHour will update this story as it develops.
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