U.S. approves first marijuana plant-derived drug for epilepsy

Posted June 27, 2018

For the first time, the FDA approved a drug derived from the marijuana plant, and it could help patients with rare forms of epilepsy.

Following a successful trial in May that proved the drug reduced seizure frequency by 40 percent, Epidolex will become the first FDA-approved medicine to include cannabidiol, or CBD, a non-psychoactive chemical found in the marijuana plant.

Many parents already are giving children unregulated CBD formulations that are available in medical marijuana dispensaries in the many states where such operations are legal.

GW Pharmaceuticals, the British company responsible for the drug, said now approved AEDs (anti-epileptic drugs) are not always effective in the majority of patients with Lennox-Gastaut Syndrome (LGS) and Dravet syndrome - severe forms of childhood-onset epilepsy.

Gareth Southgate says England must focus on Panama and forget VAR verdicts
Panama will look to their superstar Roman Torres who Captains the side and scored the goal that got them to the World Cup . If we keep the ball, keep to the style we've been playing, I think we'll be fine".

"For those living with intractable seizures caused by LGS and Dravet syndrome, Epidiolex represents a true medical advancement", said Philip Gattone, president and CEO of the Epilepsy Foundation. "But it's also important to note that this is not an approval of marijuana or all of its components".

Now with the approval of Epidiolex, a drug that will not produce an euphoric "high" feeling in the user - Devinsky said he expected CBD would be moved down to a schedule 4 or 5 drug, which is one that poses a low potential for abuse and dependence. "And, the FDA is committed to this kind of careful scientific research and drug development", FDA Commissioner Scott Gottlieb, M.D, said. This is not only the first drug that contains substances from marijuana, but it is also the first drug aimed to treat Dravet syndrome.

"I preferred this to some of those other options because it's is a commercial product that has gone through rigorous testing", said Hendershot, who lives in Rochester, New York.

Dravet syndrome is a rare genetic condition that usually shows up in infants, starting with fever-related seizures and progressing to other, more severe seizure types.

The 23 best World Cup players after the first round of action
U.S. national security adviser John Bolton plans to visit Moscow next week to prepare for a possible meeting of U.S. Fulfilling a long-standing personal invitation from Putin to attend the World Cup, Blatter will travel to St.

The approval could spur more research into marijuana products, though marijuana itself remains illegal.

The FDA previously issued warnings to CBD producers that claimed their products could treat specific diseases, such as cancer or Alzheimer's.

Epidiolex is also the first prescription created to treat children with Dravet syndrome, according to the FDA's announcement.

The FDA is not required to follow the advisory panel's advice but usually does.

Suns might try to trade No. 1 pick for Kawhi Leonard
The source suggested that the Spurs' decision to make public that Leonard was cleared to play essentially "hung him out to dry". In today's National Basketball Association , if star players want to get together then they will move mountains to do it.

That's according to Steve Fox, the director of VS Strategies, which was retained by GW Pharmaceuticals to assist with lobbying and public relations efforts. Shinnar said he will welcome approval of a medicine that had undergone stringent FDA review for safety and effectiveness. And it was based on well-controlled clinical trials evaluating the use of this compound in the treatment of a specific condition. But GW said it expects that the DEA will reschedule CBD within 90 days. The administration would then presumably reclassify cannabidiol in a less restrictive schedule (the DEA has five drug schedules, with Schedule I being the most restrictive and Schedule V being the least restrictive). "This is how sound medical science is advanced".